Category: Uncategorized
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Construct Validity Supported for Multiple DMOs
Categories: UncategorizedA recent webinar hosted by members of the Mobilise-D consortium revealed that construct validity was supported for multiple digital mobility outcomes (DMOs). The clinical validation studies involved almost 2,400 patients and evaluated 24 DMOs across 4 participant cohorts: chronic obstructive pulmonary disease (COPD), multiple sclerosis (MS), Parkinson’s (PD), and proximal femur fracture (PFF). Construct validity
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How Real-World Mobility Data Can Improve Pharma R&D Productivity
Categories: UncategorizedProductivity in biopharmaceutical R&D is driven by a combination of effectiveness (doing the right things) and efficiency (doing things right). The framework below was recently presented by Roche at the recent Digital Biomarkers conference in Basel, and illustrates a number of levers firms can use to improve productivity. We have used it to show how
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Why Mobility is the 6th Vital Sign
Categories: UncategorizedWalking is something most of us take for granted. That belies the fact that it is an incredibly complex activity, requiring dynamic interactions between multiple systems throughout the body. With all systems fully functional, the brain takes in visual information on your surroundings, while the vestibular system helps keep the body in balance. The somatosensory
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How to Measure Mobility in the Real World
Categories: UncategorizedNote: This is an abridged version our white paper on ‘How to Measure Mobility in the Real World’. To see the full paper with additional results, comprehensive references and more detail on the methodology, please download the paper on our website here. Measuring Real-World Mobility with the Mobilise-D Method The Mobilise-D project represented a major step forward in
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How are Mobility Endpoints Used in Pivotal Clinical Trials?
Categories: UncategorizedMobility loss is common, with about 1 billion people globally living with some form of mobility loss as a result of respiratory, cardiovascular, musculoskeletal, neurological or other issues. Its consequences are severe and go well beyond the physical. Loss of mobility can also have a profound impact on a person’s mental health, social role, social life and even
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Why Measuring Real-World Mobility Matters
Categories: UncategorizedNote: This is the executive summary of our white paper on Why Measuring Real World Mobility Matters. To see the full paper with a comprehensive set of references, please download the paper here. Mobility loss is common, and the implications are profound Mobility loss is common, with 32% of adults over 75 in the EU
